Pathophysiology is the science of the general principles of the onset, development and outcome of a disease. 

The main goal of pathophysiology as an academic discipline is to lay the theoretical foundations for students to understand the peculiarities of etiology, pathogenesis and clinical manifestations of the disease. 

Pathophysiology consists of two sections: 

- General nosology, typical pathological processes - contains the basic provisions of the doctrine of disease, etiology and pathogenesis, reveals the essence of the pathogenic effects of environmental and internal factors, typical pathological processes.

- Pathophysiology of organs and systems - involves the study of the basic patterns of functional and structural disorders and changes that occur under the influence of pathogenic factors, and the general patterns of development of diseases of individual organs and systems that occur in clinical practice.

The subject of study of the discipline is general laws, primarily of a functional nature, which study the course of the disease, mechanisms of resistance, recovery and completion of the disease.

Interdisciplinary connections: The content of the program in clinical pathophysiology involves the use of knowledge, skills and abilities in normal anatomy and physiology, pathological anatomy, medical biology, microbiology, medical informatics, basic biophysics, biochemistry, medical genetics, pharmacology, epidemiology and principles of evidence-based medicine, emergency and urgent care, history of medicine, philosophy. In turn, the knowledge of pathophysiology is professionally integrated into special clinical disciplines. The study of the discipline involves the use of skills and abilities of search, critical perception, analysis and evaluation of information sources, discussion, dialogue, oral and written argumentation, public speaking in the study of related disciplines during the 4th year of study; is the basis for preparation for the USQE licensing exam, preparation for study in higher education institutions in the programs of the third educational and scientific level of higher education.

Reference

Силабус  навчальної дисципліни «Патологічна фізіологія» / Кафедра патологічної фізіології ім. Д. О. Альперна / Харківський національний медичний університет. – 2020.